School of Pharmacy - School of Pharmacy

  • Professor Toxicology
  • LEE, SANGKYU
    Lab Toxicoproteomics

Research Interest

Toxicoproteomics
Protein post-translational modification
Drug metabolism
 Integrative omics

Education

  • 2004-2007 College of Pharmacy, Yeungnam University, Ph.D. Pharmacy

Experience

  • 2007-2009 KIST, Doping control center, Post-doc
  • 2009-2011 The University of Chicago, Ben May Department, Post-doc
  • 2011-2023 Kyungpook National University, College of Pharmacy, Professor

Journal Articles

  • (2024)  p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL.  NATURE METABOLISM.  6, 
  • (2023)  Global profiling of lysine acetylation and lactylation in Kupffer cells.  JOURNAL OF PROTEOME RESEARCH.  22,  12
  • (2023)  Identification of α-amanitin effector proteins in hepatocytes by limited proteolysis-coupled mass spectrometry.  CHEMICO-BIOLOGICAL INTERACTIONS.  386, 
  • (2023)  Using Comparative Proteomics to Identify Protein Signatures in Clear Cell Renal Cell Carcinoma.  CANCER GENOMICS & PROTEOMICS.  20,  6
  • (2023)  Integrative multi-omics reveals analogous developmental neurotoxicity mechanisms between perfluorobutanesulfonic acid and perfluorooctanesulfonic acid in zebrafish.  JOURNAL OF HAZARDOUS MATERIALS.  457, 
  • (2023)  Identification of Histone Lysine Acetoacetylation as a Dynamic Post-Translational Modification Regulated by HBO1.  ADVANCED SCIENCE.  10,  25
  • (2023)  Integrative profiling of lysine acylome in sepsis-induced liver injury.  JOURNAL OF PROTEOME RESEARCH.  22,  9
  • (2023)  p21-activated kinase 4 suppresses fatty acid b-oxidation and ketogenesis by phosphorylating NCoR1.  NATURE COMMUNICATIONS.  14,  1
  • (2023)  Insights into the mechanisms of within-species variation in sensitivity to chemicals: A case study using daphnids exposed to CMIT/MIT biocide.  ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.  258,  114967
  • (2023)  LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer.  GENOMICS PROTEOMICS & BIOINFORMATICS.  21,  1